Abstract Background Mitotic catastrophe is well-known as a major pathway of endogenous tumor death, but the prognostic Mirrror significance of its heterogeneity regarding bladder cancer (BLCA) remains unclear.Methods Our study focused on digging deeper into the TCGA and GEO databases.Through differential expression analysis as well as Weighted Gene
Pseudomonas PA14H7: Identification and Quantification of the 7-Hydroxytropolone Iron Complex as an Active Metabolite against Dickeya, the Causal Agent of Blackleg on the Potato Plant
Soft rot Pectobacteriaceae (SRP), Scissors such as Pectobacterium and Dickeya, are phytopathogenic agents responsible for blackleg disease on several crops, such as potatoes, affecting the yield and depressing the seed production quality.However, neither conventional nor biocontrol products are available on the market to control this disease.In thi
FEAST: A flow cytometry-based toolkit for interrogating microglial engulfment of synaptic and myelin proteins
Abstract Although engulfment is a hallmark of microglia function, fully validated platforms that facilitate high-throughput quantification of this process are lacking.Here, we present FEAST (Flow cytometric Engulfment Assay for Specific Balloon Arch Target proteins), which enables interrogation of in vivo engulfment of synaptic material by brain re
Could the FDA-approved anti-HIV PR inhibitors be promising anticancer agents? An answer from enhanced docking approach and molecular dynamics analyses
Olayide A Arodola, Mahmoud ES SolimanMolecular Modelling and Drug Design Lab, School of Health Sciences, Westville Campus, University of KwaZulu-Natal, Durban, South AfricaAbstract: Based on experimental data, the anticancer activity of nelfinavir (NFV), a US Food and Drug Administration (FDA)-approved HIV-1 protease inhibitor (PI), was reported.Ne
Effective atomic numbers and electron density of dosimetric material
A novel method for determination of mass attenuation coefficient of x-rays employing NaI (Tl) detector system and radioactive sources is described.in this paper.A rigid geometry arrangement and gating of the spectrometer at FWHM position and selection of absorber foils are all DOG WAST BAGS done following detailed investigation, to minimize the eff